Your browser is unsupported

We recommend using the latest version of IE11, Edge, Chrome, Firefox or Safari.

Scientific Summary

Almost half of children 11 years old and younger suffer from dental caries, making caries one of the most common chronic diseases of childhood. Low-income and minority children bear a disproportionate portion of this burden. In Chicago, these disparities are obvious, with 63% of Chicago-area 3rd-graders having dental caries and over half of those caries untreated. Pediatric dental caries are associated with pain, more severe infections, malnutrition, speech difficulties, poor school performance, cosmetic problems, and an overall lower quality of life.

While many oral health interventions have been developed to reduce the incidence of caries, even the most successful programs have limited effectiveness in high risk children. The delivery and receipt of proper preventive oral healthcare involves social and environmental factors that operate on individual, family, and community levels. Multi-level interventions recognize the need to target these levels simultaneously but multi-level oral health interventions for the primary prevention of dental caries are lacking.

COordinated Oral health Promotion (CO-OP) Chicago was one of nine studies in the Oral Health Disparities and Inequities Research Consortium, and one of four studies selected to test oral health interventions. The Consortium, funded by the National Institute of Dental and Craniofacial Research Consortium, aims to reduce inequities in access to care and oral health disparities of U.S. children. Consortium studies are supported by a single data coordinating center.

CO-OP Chicago brings together a team of clinical pediatricians and dentists, researchers, health psychologists, and policy experts to rigorously test the ability of an oral health promotion intervention to improve child and family oral health. The primary intervention is family-focused education and support from community health workers (CHWs); this intervention will be applied in a range of settings to determine which settings, or combination of settings, result in the best outcomes.

UH2 Phase [NIDCR UH2DE02583]
The aim of the UH2 Phase was to formalize partnerships and finalize study design and protocol, including:
1) A formative assessment to determine partner operations, resources, and needs;
2) Training of community health workers (CHWs);
3) Pilot testing of recruitment and intervention protocols;
4) Creation of a final Manual of Procedures; and
5) Clearances and signed contracts from all institutional and community partners.

UH3 Phase [NIDCR UH3DE025483]
The UH3 Phase then implemented and evaluated the CHW intervention in clinics, WIC sites, and individual families. The aims of this phase were to do the following:

Primary Aim: To evaluate the efficacy of a one-year oral health CHW intervention, compared to usual care, to improve self- reported brushing frequency and observed plaque score in low income urban children under the age of 3 years old. The scientific team hypothesized that receipt of CHW intervention will be associated with improved behaviors at 12-months compared to usual care.

Exploratory Aim: To determine if the oral health CHW intervention impact on child brushing behaviors varied when the intervention is delivered out of a medical clinic compared to a community WIC center.

The trial is registered on

COVID-19 Supplement [NIDCR UH3DE05483-05S1]
We received additional support to study the impact of COVID-19 on oral health. COVID-19 brought new changes to household dynamics and unforeseen stressors to families already experiencing oral health disparities. The medical clinics and social service agencies that service these families were also majorly affected. This supplement aimed to determine specific intervention needs regarding dental care access, oral health behaviors, nutrition, and mental health for CO-OP Chicago families and communities following COVID-19.

CO-OP Chicago Cohort Study [NIDCR U01DE030067]
The CO-OP Chicago Cohort Study transitions trial participants and newly enrolled families into a longitudinal cohort to determine predictors of oral health behaviors and caries risk in low-income, urban young children over time.